Sinoway Industrial Co., Ltd

Date: 13th May 2016
Chlortetracycline Hcl
Sinoway Industrial Co.,Ltd is a famous China chlortetracycline hcl manufacturer and supplier,Website:http://www.sinoway-chem.com, welcome to buy GMP and EP chlortetracycline hcl from us and check the price with us.Basic information of Chlortetracycline HCL:NameChlortetracycline HCLCAS :64-72-2Molecular FormulaC22H24Cl2N2O8Molecular Weight515.34QualityStandardEP8Package SizeFor small quantity: Double plastic bag inside ,Aluminum foil bag outsideFor commercial quantity: 25kg fiber drum & Aluminum tinBrief IntroductionA yellow powder, slightly soluble in water and in calcohol. Dissoves in solutions of alkali hydroxides and carbonates.This product is a tetracyclic broad-spectrum antibiotics against Gram-positive and negative bacteria and Chlamydia, mycoplasma, rickettsia were inhibited. For pullorum, typhoid fever, swine, and poultry paratyphoid bacterial enteritis, cholera and other diseases. Amount of feed not only from the long-term treatment of the role of prevention, to improve the survival rate of livestock, egg production, promote growth and development Zhuo have a good effect.Use of Chlortetracycline HCL:Animal antibioticsCOA ofChlortetracycline HCL:CERTIFICATE ON ANALYSISName of productChlortetracycline HCLBatch of No.H20150602Manufacture Date02,Jun.,2015Report Date07,Jun.2015Exp. Date01.Jun.2019ItemsSpecificationResultsAppearanceYellow powderConformIdentificationA(Current Ph.Eur.2.2.27)Thin-Layer ChromatographyPositiveB(Current Ph.Eur.0173)The colour becomes brownishPositiveC(Current Ph.Eur.2.3.1)It gives reaction (a) of chloridesPositiveD(Current Ph.Eur.2.2.29)Liquid chromatographyPositivepH(Current Ph.Eur.2.2.32.3-3.32.69Specific Optical Rotation(Current Ph. Eur 2.2.7)-250?~ -235??anhydrous substance?-241?Absorbance(Current Ph. Eur.2.2.25)?0.40,460nm0.255Related substances(Current Ph. Eur.2.2.29)Impurity A(4-epichlortetracycline?4.0%1.09%Impurity B(demeclocycline)?1.0%0.19%Impurity E(4-epidemethylchlortetracycline)?1.0%0.61%Impurity J(anhydrotetracycline)?0.3%0.07%Impurities D(4-epitetracycline)?0.2%?0.05%Impurities G(isochlortetracycline)?0.2%Not detectedImpurities H(2-acetyl-2-decarboxamidochlortetracycline)?0.2%0.09%Impurities L(anhydrochlortetracycline)?0.2%0.12%Impurities K(4-epianhydrochlortetracycline)?0.15%Not detectedUnspecified ImpuritiesImpurities C(4-epidemethyltetracycline)?0.10%Note detectedImpurities F(4-epiisochlortetracycline)?0.10%Not detectedImpurities I(4-epianhydrotetracycline)?0.10%Not detectedDisregard limit(Other Unknown)?0.05%ConformSum of impurities other than A?2.0%1.08%Heavy Metals(Current Ph. Eur 2.4.8)?50ppm?50ppmWater(Current Ph. Eur. 2.5.12)?2.0%0.52%Sulfated ash(Current Ph. Eur.2.4.14)?0.5%0.12%Assay(Current Ph. Eur.2.2.29)Chlortetracycline hydrochloride(CTC.HCL)?89.5%?anhydrous substance?91.48%Tetracycline hydrochloride(TC.HCL)?6.0%?anhydrous substance4.68%CTC.HCL.+TC.HCL94.5-102.0%(anhydrous substance96.16%Ethanol(SOP)?0.5%?GC?0.35%ConclusionConform to EP8
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