Sinoway Industrial Co., Ltd

Date: 16th August 2016
GMP factory supply Rapamycin / Sirolimus CAS No: 53123-88-9
Sinoway Industrial Co.,Ltd is a famous China rapamycin manufacturer and supplier, welcome to buy GMP and EP rapamycin from us and check the price with us.1.Quick details of Rapamycin ( Sirolimus ):Product name: RapamycinOther name:SirolimusCAS No: 53123-88-9Molecular Formula : C51H79NO13Molecular Weight: : 914.18Appearance: off-white to yellow crystalline powderPurity: 99% min2. COA of Rapamycin:TEST ITEMSSPECIFICATIONRESULTSAppearanceWhite or off-white crystal powder, odorlessConformIdentificationIR spectrum is concordant with reference spectrum of Sirolimus RS.ConformHPLC?The retention time is complied with that of reference substance.ConformWater?2.0%0.2%Heavy metals?20 ppm<20ppmChromtographic purityIsomer A?1.0%0.2 %Isomer C?5.0%1.9 %Any other individual impurity?0.5 %0.3 %Total impurity?Excluding isomerA&C??3.0?0.5%Assay(dried substance)98.0% ~ 102.0%99.4%Residual solventsn-Hexane ?290ppm<290ppmAcetone ?5000ppm<5000ppmAcetoacetate ?5000ppm<5000ppmButyl Acetate ?5000ppm<5000ppm3.Application ofRapamycin / Sirolimus:Rapamycin is a triene macrolide antibiotic, which demonstratesanti-fungal, anti-inflammatory, anti-tumor and immunosuppressive properties. Rapamycin has been shown to block T-cell activation and proliferation, as well as, the activation of p70 S6 kinase and exhibits strong binding to FK-506 binding proteins. Rapamycin also inhibits the activity of the protein, mTOR, (mammalian target of rapamycin) which functions in a signaling pathway to promote tumor growth. Rapamycin binds to a receptor protein (FKBP12) and the rapamycin/FKB12 complex then binds to mTOR and prevents interaction of mTOR with target proteins in this signaling pathway.More details pls contact with me......Ms. Serein YanInternational Sales Department-----------------------------------------------------------------------Sinoway Industrial Co., Ltd.? (29 years, ISO9001:2008 and SGS certified) Website:?www.sinoway-chem.com? / www.sinowaychem.com Add: 16/F., Huicheng Comm. Complex, No.839 Xiahe Rd, Xiamen, China (Postal Code: 361004)Tel: 0086-592-5887162? Fax: 0086-592-5854960E-mail: serein@china-sinoway.comSkype:?serein95?? ,?Mobile/ Wechat / Whats App: 0086-15060741657
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